What is the most important information I should know about celecoxib? Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.

What is celecoxib?

Celecoxib is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Celecoxib works by reducing substances that cause inflammation, pain, and fever in the body.
Celecoxib is used to reduce pain, inflammation, and stiffness caused by osteoarthritis and rheumatoid arthritis. Celecoxib is also used to reduce the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), to treat acute pain, and to treat pain associated with menstruation. Celecoxib may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about rofecoxib?

Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; blood in your vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of your skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.

What is rofecoxib?

Rofecoxib is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Rofecoxib works by reducing substances that cause inflammation, pain, and fever in the body.
Rofecoxib is used to reduce pain, inflammation, and stiffness caused by osteoarthritis; to manage pain in adults; and to treat menstrual pain.

Rofecoxib may also be used for purposes other than those listed in this medication guide.